2,4-Dichloro-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-phenylalanin
N-(tert-Butoxycarbonyl)-2,4-dichloro-L-phenylalanine
CAS: 114873-04-0
Molecular Formula: C14H17Cl2NO4
2,4-Dichloro-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-phenylalanin - Names and Identifiers
| Name | N-(tert-Butoxycarbonyl)-2,4-dichloro-L-phenylalanine |
| Synonyms | RARECHEM BK PT 0110 Boc-Phe(2,4-Cl2)-OH Boc-2,4-Dichloro-D-phenylalanine (R)-BOC-2,4-DICHLOROPHENYLALANINE Boc-Phe(2,4-Cl2)-OH Boc-2,4-Dichloro-L-Phenylalanin (S)-Boc-2-amino-3-(2,4-dichlorophenyl)propionic acid N-(tert-Butoxycarbonyl)-2,4-dichloro-L-phenylalanine 2,4-Dichloro-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-phenylalanin (S)-2-((tert-Butoxycarbonyl)aMino)-3-(2,4-dichlorophenyl)propanoic acid |
| CAS | 114873-04-0 |
| InChI | InChI=1S/C14H17Cl2NO4/c1-14(2,3)21-13(20)17-11(12(18)19)6-8-4-5-9(15)7-10(8)16/h4-5,7,11H,6H2,1-3H3,(H,17,20)(H,18,19)/t11-/m0/s1 |
2,4-Dichloro-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-phenylalanin - Physico-chemical Properties
| Molecular Formula | C14H17Cl2NO4 |
| Molar Mass | 334.2 |
| Density | 1.323±0.06 g/cm3(Predicted) |
| Melting Point | 133-137°C |
| Boling Point | 476.1±45.0 °C(Predicted) |
| Appearance | Light brown powder |
| pKa | 3.78±0.12(Predicted) |
| Storage Condition | 2-8°C |
| MDL | MFCD01862942 |
2,4-Dichloro-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-phenylalanin - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S37/39 - Wear suitable gloves and eye/face protection S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| WGK Germany | 3 |
| HS Code | 29223900 |
| Hazard Class | IRRITANT |
2,4-Dichloro-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-phenylalanin - Introduction
BOC-L-2, 4-dichlorophenylalanine is an organic compound having the formula BOC-Cl-C6H3-CH2-CH(NH2)-COOH. The following is a description of its nature, use, preparation and safety information:
Nature:
BOC-L-2, 4-dichlorophenylalanine is a white crystal or crystalline powder with a high melting point and boiling point. It is stable at room temperature, insoluble in water, but soluble in organic solvents such as ethanol, dimethylformamide, etc.
Use:
BOC-L-2, 4-dichlorophenylalanine is commonly used as a protecting group in organic synthesis. It can achieve the specific purpose of organic synthesis by protecting the amino group to prevent it from being affected by other reactants. In addition, it can also be used for drug synthesis and peptide synthesis in the field of medicine.
Method:
BOC-L-2, the preparation of 4-dichlorophenylalanine can be achieved by reacting L-2, 4-dichlorophenylalanine with BOC-Cl. The reaction is usually carried out in an organic solvent, such as dimethylformamide or chloroform, with the addition of an appropriate amount of a base to catalyze the reaction.
Safety Information:
BOC-L-2, safety precautions for 4-dichlorophenylalanine include:
1. the compound may be irritating to the eyes, skin and respiratory system, the operation should pay attention to protective measures, avoid direct contact.
2. During use, ensure good ventilation and use personal protective equipment, such as laboratory gloves and protective glasses.
3. It should be kept away from flammables and high temperatures, and should be kept cold, dry and sealed during storage.
4. When using or disposing of the compound, the safe operation procedures and correct disposal methods of professional laboratories should be observed.
It should be noted that, BOC-L-2, 4-dichlorophenylalanine is a chemical reagent, which is mainly used in the field of laboratory research and synthetic chemistry. Please understand its properties and safe operation requirements in detail before use, and operate under professional guidance.
Nature:
BOC-L-2, 4-dichlorophenylalanine is a white crystal or crystalline powder with a high melting point and boiling point. It is stable at room temperature, insoluble in water, but soluble in organic solvents such as ethanol, dimethylformamide, etc.
Use:
BOC-L-2, 4-dichlorophenylalanine is commonly used as a protecting group in organic synthesis. It can achieve the specific purpose of organic synthesis by protecting the amino group to prevent it from being affected by other reactants. In addition, it can also be used for drug synthesis and peptide synthesis in the field of medicine.
Method:
BOC-L-2, the preparation of 4-dichlorophenylalanine can be achieved by reacting L-2, 4-dichlorophenylalanine with BOC-Cl. The reaction is usually carried out in an organic solvent, such as dimethylformamide or chloroform, with the addition of an appropriate amount of a base to catalyze the reaction.
Safety Information:
BOC-L-2, safety precautions for 4-dichlorophenylalanine include:
1. the compound may be irritating to the eyes, skin and respiratory system, the operation should pay attention to protective measures, avoid direct contact.
2. During use, ensure good ventilation and use personal protective equipment, such as laboratory gloves and protective glasses.
3. It should be kept away from flammables and high temperatures, and should be kept cold, dry and sealed during storage.
4. When using or disposing of the compound, the safe operation procedures and correct disposal methods of professional laboratories should be observed.
It should be noted that, BOC-L-2, 4-dichlorophenylalanine is a chemical reagent, which is mainly used in the field of laboratory research and synthetic chemistry. Please understand its properties and safe operation requirements in detail before use, and operate under professional guidance.
Last Update：2024-04-09 19:05:45
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